Spontaneous excitatory transmission enhancement produced by linalool and its isomer geraniol in rat spinal substantia gelatinosa neurons - involvement of transient receptor potential channels
Chong Wang; Tsugumi Fujita; Hiroki Yasuda; Eiichi Kumamoto
Phytomedicine Plus, Feb. 2022, Reviewed

Direct evidence of edge-to-face CH/π interaction for PAR-1 thrombin receptor activation.
Daisuke Asai; Naoko Inoue; Makiko Sugiyama; Tsugumi Fujita; Yutaka Matsuyama; Xiaohui Liu; Ayami Matsushima; Takeru Nose; Tommaso Costa; Yasuyuki Shimohigashi
Bioorganic & medicinal chemistry, Dec. 2021, Reviewed

PCBP1 and PCBP2 both bind heavily oxidized RNA but cause opposing outcomes, suppressing or increasing apoptosis under oxidative conditions
Takashi Ishii; Tatsuhiro Igawa; Hiroshi Hayakawa; Tsugumi Fujita; Mutsuo Sekiguchi; Yusaku Nakabeppu
Journal of Biological Chemistry, Aug. 2020, Reviewed

Inhibition by general anesthetic propofol of compound action potentials in the frog sciatic nerve and its chemical structure.
Magori N; Fujita T; Mizuta K; Kumamoto E
Naunyn-Schmiedeberg's archives of pharmacology, Mar. 2019, Reviewed, No invitation

Moieties of plant-derived compounds responsible for outward current production and TRPA1 activation in rat spinal substantia gelatinosa.
Wang C; Yu T; Fujita T; Kumamoto E
Pharmacological reports : PR, Feb. 2019, Reviewed, No invitation

Inhibition by O-desmethyltramadol of glutamatergic excitatory transmission in adult rat spinal substantia gelatinosa neurons.
Koga A; Fujita T; Piao LH; Nakatsuka T; Kumamoto E
Molecular pain, Jan. 2019, Reviewed, No invitation

Orexin B Modulates Spontaneous Excitatory and Inhibitory Transmission in Lamina II Neurons of Adult Rat Spinal Cord
Chong Wang; Tsugumi Fujita; Eiichi Kumamoto
Neuroscience, Jul. 2018, Reviewed, No invitation

Inhibition by non-steroidal anti-inflammatory drugs of compound action potentials in frog sciatic nerve fibers
Rika Suzuki; Tsugumi Fujita; Kotaro Mizuta; Eiichi Kumamoto
Biomedicine and Pharmacotherapy, Jul. 2018, Reviewed, No invitation

Modulation by orexin A of spontaneous excitatory and inhibitory transmission in adult rat spinal substantia gelatinosa neurons
Chong Wang; Tsugumi Fujita; Eiichi Kumamoto
Biochemical and Biophysical Research Communications, Jun. 2018, Reviewed, No invitation

Compound action potential inhibition produced by various antidepressants in the frog sciatic nerve
Ryo Hirao; Tsugumi Fujita; Aiko Sakai; Eiichi Kumamoto
European Journal of Pharmacology, Jan. 2018, Reviewed, No invitation

Hinokitiol inhibits compound action potentials in the frog sciatic nerve
Nobuya Magori; Tsugumi Fujita; Eiichi Kumamoto
European Journal of Pharmacology, Jan. 2018, Reviewed, No invitation

Bisphenol A inhibits compound action potentials in the frog sciatic nerve in a manner independent of estrogen receptors
Kotaro Mizuta; Tsugumi Fujita; Hiroki Yamagata; Eiichi Kumamoto
Biochemistry and Biophysics Reports, Jul. 2017, Reviewed, No invitation

Presynaptic facilitation by tetracaine of glutamatergic spontaneous excitatory transmission in the rat spinal substantia gelatinosa Involvement of TRPAI channels
Lian-Hua Piao; Tsugumi Fujita; Ting Yu; Eiichi Kumamoto
BRAIN RESEARCH, Feb. 2017, Reviewed, No invitation

Developmental change and sexual difference in synaptic modulation produced by oxytocin in rat substantia gelatinosa neurons
Chang-Yu Jiang; Tsugumi Fujita; Eiichi Kumamoto
Biochemistry and Biophysics Reports, Sep. 2016, Reviewed, No invitation

1,8-and 1,4-cineole enhance spontaneous excitatory transmission by activating different types of transient receptor potential channels in the rat spinal substantia gelatinosa
Chang-Yu Jiang; Chong Wang; Nian-Xiang Xu; Tsugumi Fujita; Yuzo Murata; Eiichi Kumamoto
JOURNAL OF NEUROCHEMISTRY, Feb. 2016, Reviewed, No invitation

Traditional Japanese medicines inhibit compound action potentials in the frog sciatic nerve
Akitomo Matsushita; Tsugumi Fujita; Sena Ohtsubo; Eiichi Kumamoto
JOURNAL OF ETHNOPHARMACOLOGY, Feb. 2016, Reviewed, No invitation

Enhancement by citral of glutamatergic spontaneous excitatory transmission in adult rat substantia gelatinosa neurons
Lan Zhu; Tsugumi Fujita; Chang-Yu Jiang; Eiichi Kumamoto
NEUROREPORT, Feb. 2016, Reviewed, No invitation

Action of thymol on spontaneous excitatory transmission in adult rat spinal substantia gelatinosa neurons
Zhi-Hao Xu; Chong Wang; Tsugumi Fujita; Chang-Yu Jiang; Eiichi Kumamoto
NEUROSCIENCE LETTERS, Oct. 2015, Reviewed, No invitation

Spontaneous L-glutamate release enhancement in rat substantia gelatinosa neurons by (-)-carvone and (+)-carvone which activate different types of TRP channel
Qin Kang; Chang-Yu Jiang; Tsugumi Fujita; Eiichi Kumamoto
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, Apr. 2015, Reviewed, No invitation

Inhibition of the compound action potentials of frog sciatic nerves by aroma oil compounds having various chemical structures
Sena Ohtsubo; Tsugumi Fujita; Akitomo Matsushita; Eiichi Kumamoto
Pharmacology Research and Perspectives, Mar. 2015, Reviewed, No invitation

Tymol modulates spontaneous excitatory transmission in adult rat spinal substantia gelatinosa neurons
Z.-H.Xu; C.-Y.Jiang; T.Fujita; L.Zhu; C.Wang; E.Kumamoto
Journal of Functional Diagnosis of the Spinal Cord, 2015, Reviewed, No invitation

Spontaneous excitatory transmission enhancement through transient receptor potential channel activation by carvone in the rat spinal substantia gelatinosa
Q.Kang; C.-Y.Jiang; T.Fujita; L.Zhu; E.Kumamoto
Journal of Functional Diagnosis of the Spinal Cord, 2015, Reviewed, No invitation

Cellular mechanisms for antinociception produced by neuropeptides in the rat spinal dorsal horn
E.Kumamoto; T.Fujita
Current Topics in Peptide & Protein Research, 2015, Reviewed, No invitation

Anandamide depresses glycinergic and GABAergic inhibitory transmission in adult rat substantia gelatinosa neuron
Y.Kawasaki; T.Fujita; K.Yang; E.Kumamoto
Pharmacology & Pharmacy, 2015, Reviewed, No invitation

Canracrol presynaptically enhances spontaneous excitatory transmission and produces outward current in adult rat spinal substantia gelatinosa neurons
Qing-Tian Luo; Tsugumi Fujita; Chang-Yu Jiang; Eiichi Kumamoto
BRAIN RESEARCH, Dec. 2014, Reviewed, No invitation

Synaptic modulation and inward current produced by oxytocin in substantia gelatinosa neurons of adult rat spinal cord slices
Chang-Yu Jiang; Tsugumi Fujita; Eiichi Kumamoto
JOURNAL OF NEUROPHYSIOLOGY, Mar. 2014, Reviewed, No invitation

Actions of oxytocin on rat spinal dorsal horn lamina II neurons – cellular mechanisms for antinociception
C.-Y.Jiang; T.Fujita; Z.-H.Xu; S.Ohtsubo; A.Matsushita; E.Kumamoto
Pain Research, 2014, Reviewed, No invitation

Analysis of inward current produced by oxytocin in adult rat spinal substantia gelatinosa neurons
C.-Y.Jiang; T.Fujita; S.Ohsubo; A.Matsushita; Z.-H.Xu; E.Kumamoto
Journal of Functional Diagnosis of the Spinal Cord, 2014, Reviewed, No invitation

Effects of Various Antiepileptics Used to Alleviate Neuropathic Pain on Compound Action Potential in Frog Sciatic Nerves: Comparison with Those of Local Anesthetics
Yuhei Uemura; Tsugumi Fujita; Sena Ohtsubo; Naomi Hirakawa; Yoshiro Sakaguchi; Eiichi Kumamoto
BIOMED RESEARCH INTERNATIONAL, 2014, Reviewed, No invitation

Zingerone enhances glutamatergic spontaneous excitatory transmission by activating TRPA1 but not TRPV1 channels in the adult rat substantia gelatinosa
Hai-Yuan Yue; Chang-Yu Jiang; Tsugumi Fujita; Eiichi Kumamoto
JOURNAL OF NEUROPHYSIOLOGY, Aug. 2013, Reviewed, No invitation

Inhibition by TRPA1 agonists of compound action potentials in the frog sciatic nerve
Akitomo Matsushita; Sena Ohtsubo; Tsugumi Fujita; Eiichi Kumamoto
Biochemical and Biophysical Research Communications, Apr. 2013, Reviewed, No invitation

Inhibition by menthol and its related chemicals of compound action potentials in frog sciatic nerves
Hiroki Kawasaki; Kotaro Mizuta; Tsugumi Fujita; Eiichi Kumamoto
LIFE SCIENCES, Mar. 2013, Reviewed, No invitation

Inhibition by capsaicin and its related vanilloids of compound action potentials in frog sciatic nerves
Daisuke Tomohiro; Kotaro Mizuta; Tsugumi Fujita; Yukiko Nishikubo; Eiichi Kumamoto
LIFE SCIENCES, Mar. 2013, Reviewed, No invitation

Enhancement by interleukin-1 beta of AMPA and NMDA receptor-mediated currents in adult rat spinal superficial dorsal horn neurons
Tao Liu; Chang-Yu Jiang; Tsugumi Fujita; Shi-Wen Luo; Eiichi Kumamoto
MOLECULAR PAIN, Mar. 2013, Reviewed, No invitation

Inhibition by morphine and its analogs of action potentials in adult rat dorsal root ganglion neurons
Kotaro Mizuta; Tsugumi Fujita; Eiichi Kumamoto
JOURNAL OF NEUROSCIENCE RESEARCH, Sep. 2012, Reviewed, No invitation

PRESYNAPTIC ENHANCEMENT BY EUGENOL OF SPONTANEOUS EXCITATORY TRANSMISSION IN RAT SPINAL SUBSTANTIA GELATINOSA NEURONS IS MEDIATED BY TRANSIENT RECEPTOR POTENTIAL A1 CHANNELS
M. Inoue; T. Fujita; M. Goto; E. Kumamoto
NEUROSCIENCE, May 2012, Not reviewed, No invitation

Inhibition by menthol and its analogs of compound action potentials in frog sciatic nerves
KAWASAKI Hiroki; MIZUTA Kotaro; FUJITA Tsugumi; KUMAMOTO Eiichi
Pain Res., Mar. 2012, Reviewed, No invitation

Actions of a novel water-soluble benzodiazepine-receptor agonist JM-1232(-) on synaptic transmission in adult rat spinal substantia gelatinosa neurons
Satoko Uemura; Tsugumi Fujita; Yoshiro Sakaguchi; Eiichi Kumamoto
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, Feb. 2012, Reviewed, No invitation

Effects of oxytocin on adult rat spinal substantia gelatinosa neurons
C.-Y.Jiang; T.Fujita; L.Yang; K.Mizuta; M.Inoue; H.Kawasaki; N.-X. Xu; A.Matsushita; T.Liu; E.Kumamoto
Journal of Functional Diagnosis of the Spinal Cord, 2012, Reviewed, No invitation

Difference between modulations by piperine and olvanil of spontaneous excitatory transmission in rat spinal substantia gelatinosa neurons
L.Yang; T.Fujita; C.-Y.Jiang; K.Mizuta; M.Inoue; H.Kawasaki; N.-X.Xu; A.Matsushita; T.Liu; E.Kumamoto
Journal of Functional Diagnosis of the Spinal Cord, 2012, Reviewed, No invitation

Regulation of nociceptive information transmitting to the spinal dorsal horn from periphery : the modulation of synaptic transmission and nerve conduction
KUMAMOTO Eiichi; FUJITA Tsugumi
Pain Research, Dec. 2011, Reviewed, No invitation

Facilitatory effect of eugenol on excitatory synaptic transmission in rat spinal substantia gelatinosa neurons
INOUE Masanari; FUJITA Tsugumi; PIAO Lian-Hua; YUE Hai-Yuan; MIZUTA Kotaro; AOYAMA Takahiro; YASAKA Toshiharu; KUMAMOTO Eiichi
PAIN RESEARCH, Aug. 2011, Reviewed, No invitation

Acetylcholine and norepinephrine mediate GABAergic but not glycinergic transmission enhancement by melittin in adult rat substantia gelatinosa neurons
Tao Liu; Tsugumi Fujita; Eiichi Kumamoto
JOURNAL OF NEUROPHYSIOLOGY, Jul. 2011, Reviewed, No invitation

TRPV1 agonist piperine but not olvanil enhances glutamatergic spontaneous excitatory transmission in rat spinal substantia gelatinosa neurons
Liu Yang; Tsugumi Fujita; Chang-Yu Jiang; Lian-Hua Piao; Hai-Yuan Yue; Kotaro Mizuta; Eiichi Kumamoto
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, Jul. 2011, Reviewed, No invitation

Biphasic modulation by galanin of excitatory synaptic transmission in substantia gelatinosa neurons of adult rat spinal cord slices
Hai-Yuan Yue; Tsugumi Fujita; Eiichi Kumamoto
JOURNAL OF NEUROPHYSIOLOGY, May 2011, Reviewed, No invitation

Presynaptic facilitation by zingerone of spontaneous excitatory transmission in rat spinal substantia gelatinosa neurons
H.-Y.Yue; T.Fujita; M.Inoue; K.Mizuta; C.-Y.Jiang; L.-H.Piao; T.Yasaka; S.Uemura; L.Yang; H.Kawasaki; E.Kumamoto
Journal of Functional Diagnosis of the Spinal Cord, 2011, Reviewed, No invitation

Effect of JM 1232 (-) on excitatory and inhibitory synaptic transmission in adult rat spinal substantia gelatinosa neurons
S.Uemura; T.Fujita; H.-Y. Yue; L.-H. Piao; C.-Y.Jiang; K.Mizuta; M.Inoue; H.Kawasaki; T.Yasaka; L.Yang; E.Kumamoto
Journal of Functional Diagnosis of the Spinal Cord, 2011, Reviewed, No invitation

Effects of opioids on action potentials in rat primary-afferent neurons which terminate in the spinal dorsal horn
K.Mizuta; T.Fujita; H.-Y.Yue; C.-Y.Jiang; M.Inoue; L.-H.Piao; L.Yang; S.Uemura; H.Kawasaki; T.Yasaka; E.Kumamoto
Journal of Functional Diagnosis of the Spinal Cord, 2011, Reviewed, No invitation

In vivo patch-clamp analysis of dopaminergic antinociceptive actions on substantia gelatinosa neurons in the spinal cord
Wataru Taniguchi; Terumasa Nakatsuka; Nobuyuki Miyazaki; Hiroshi Yamada; Daisuke Takeda; Tsugumi Fujita; Eiichi Kumamoto; Munehito Yoshida
PAIN, Jan. 2011, Reviewed, No invitation

Effect of galanin on excitatory and inhibitory synaptic transmission in substantia gelatinosa neurons of rat spinal cord slices
YUE Hai-Yuan; FUJITA Tsugumi; PIAO Lian-Hua; AOYAMA Takahiro; UEMURA Satoko; NAKATSUKA Terumasa; KUMAMOTO Eiichi
Pain research : the journal of the Japanese Society for the Study of Pain = 日本疼痛学会誌, Aug. 2010, Not reviewed, No invitation

High concentrations of dexmedetomidine inhibit compound action potentials in frog sciatic nerves without alpha(2) adrenoceptor activation
Toshifumi Kosugi; Kotaro Mizuta; Tsugumi Fujita; Mikio Nakashima; Eiichi Kumamoto
BRITISH JOURNAL OF PHARMACOLOGY, Aug. 2010, Reviewed, No invitation

Excitation of rat spinal ventral horn neurons by purinergic P2X and P2Y receptor activation
Takahiro Aoyama; Syugo Koga; Terumasa Nakatsuka; Tsugumi Fujita; Masaaki Goto; Eiichi Kumamoto
BRAIN RESEARCH, Jun. 2010, Reviewed, No invitation

Activation by lidocaine of TRPA1 channels in the substantia gelatinosa of adult rat spinal cord
PIAO L.-H.
Pain Res., 2010, Not reviewed, No invitation

EFFECT OF RESINIFERATOXIN ON GLUTAMATERGIC SPONTANEOUS EXCITATORY SYNAPTIC TRANSMISSION IN SUBSTANTIA GELATINOSA NEURONS OF THE ADULT RAT SPINAL CORD
C. -Y. Jiang; T. Fujita; H. -Y. Yue; L. -H. Piao; T. Liu; T. Nakatsuka; E. Kumamoto
NEUROSCIENCE, Dec. 2009, Not reviewed, No invitation

Pre- and postsynaptic effect of galanin on excitatory synaptic transmission in rat spinal dorsal horn neurons
YUE Hai-Yuan; FUJITA Tsugumi; LIU Tao; PIAO Lian-Hua; JIANG Chang-Yu; MIZUTA Kotaro; NAKATSUKA Terumasa; KUMAMOTO Eiichi
Pain research : the journal of the Japanese Society for the Study of Pain = 日本疼痛学会誌, Aug. 2009, Not reviewed, No invitation

Proteinase-Activated Receptor-1 Activation Presynaptically Enhances Spontaneous Glutamatergic Excitatory Transmission in Adult Rat Substantia Gelatinosa Neurons
T. Fujita; T. Liu; T. Nakatsuka; E. Kumamoto
JOURNAL OF NEUROPHYSIOLOGY, Jul. 2009, Not reviewed, No invitation

TRPA1 activation by lidocaine in nerve terminals results in glutamate release increase
Lian-Hua Piao; Tsugumi Fujita; Chang-Yu Jiang; Tao Liu; Hai-Yuan Yue; Terumasa Nakatsuka; Eiichi Kumamoto
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, Feb. 2009, Reviewed, No invitation

1P-204 Presynaptic activation by local anesthetics of TRPA1 channels in the rat spinal dorsal horn(Neuroscience & Sensory systems, The 47th Annual Meeting of the Biophysical Society of Japan)
Piao Lian-Hua; Fujita Tsugumi; Jiang Chang-Yu; Mizuta Kotaro; Yue Hai-Yuan; Inoue Masanari; Kumamoto Eiichi
Seibutsu Butsuri, 2009

1P-203 Inhibitory action of bisphenol A on compound action potentials in frog sciatic nerves(Neuroscience & Sensory systems, The 47th Annual Meeting of the Biophysical Society of Japan)
Mizuta Kotaro; Fujita Tsugumi; Yamagata Hiroki; Kumamoto Eiichi
Seibutsu Butsuri, 2009

Inhibition by capsaicin and its analogs of compound action potentials in frog sciatic nerves
TOMOHIRO D.
Pain Res., 2009, Not reviewed, No invitation

Cellular mechanism for spinal cord electrical stimulation-induced analgesia
T.Nakatsuka; W.Taniguchi; Y.Kawasaki; T.Fujita; E.Kumamoto
Pain Research, 2009, Not reviewed, No invitation

Activation by lidocaine of TRP channels in the rat spinal dorsal horn
L.-H.Piao; T.Fujita; T.Liu; H.-Y.Yue; C.-Y.Jiang; K.Mizuta; D.Tomohiro; T.Nakatsuka; E.Kumamoto
Journal of Functional Diagnosis of the Spinal Cord, 2009, Not reviewed, No invitation

Inhibitory effects of opioids on compound action potentials in frog sciatic nerves and their chemical structures
Kotaro Mizuta; Tsugumi Fujita; Terumasa Nakatsuka; Eiichi Kumamoto
LIFE SCIENCES, Aug. 2008, Reviewed, No invitation

Activation of GIRK channels in substantia gelatinosa neurones of the adult rat spinal cord: a possible involvement of somatostatin
Terumasa Nakatsuka; Tsugumi Fujita; Kazuhide Inoue; Eiichi Kumamoto
JOURNAL OF PHYSIOLOGY-LONDON, May 2008, Reviewed, No invitation

Phospholipase A(2) activation enhances inhibitory synaptic transmission in rat substantia gelatinosa neurons
Tao Liu; Tsugumi Fujita; Terumasa Nakatsuka; Eiichi Kumamoto
JOURNAL OF NEUROPHYSIOLOGY, Mar. 2008, Reviewed, No invitation

2P-243 Enhancement by resiniferatoxin of glutamatergic spontaneous excitatory synaptic transmission in rat spinal dorsal horn neurons(The 46th Annual Meeting of the Biophysical Society of Japan)
Jiang Chang-Yu; Fujita Tsugumi; Liu Tao; Yue Hai-Yuan; Piao Lian-Hua; Mizuta Kotaro; Nakatsuka Terumasa; Kumamoto Eiichi
Seibutsu Butsuri, 2008

2P-244 Relationship between inhibition by opioids of compound action potentials in frog sciatic nerves and their chemical structures(The 46th Annual Meeting of the Biophysical Society of Japan)
Mizuta Kotaro; Fujita Tsugumi; Katsuki Ryo; Tomohiro Daisuke; Nakatsuka Terumasa; Kumamoto Eiichi
Seibutsu Butsuri, 2008

Inhibitory actions of opioids on compound action potentials in frog sciatic nerves
MIZUTA K.
Pain Res., 2008, Not reviewed, No invitation

Differential receptor binding characteristics of consecutive phenylalanines in mu-opioid specific peptide ligand endomorphin-2
Takeshi Honda; Naoto Shirasu; Kaname Isozaki; Michiaki Kawano; Daiki Shigehiro; Yoshiro Chuman; Tsugumi Fujita; Takeru Nose; Yasuyuki Shimohigashi
BIOORGANIC & MEDICINAL CHEMISTRY, Jun. 2007, Not reviewed, No invitation

Differential receptor binding characteristics of consecutive phenylalanines in mu-opioid specific peptide ligand endomorphin-2
Takeshi Honda; Naoto Shirasu; Kaname Isozaki; Michiaki Kawano; Daiki Shigehiro; Yoshiro Chuman; Tsugumi Fujita; Takeru Nose; Yasuyuki Shimohigashi
BIOORGANIC & MEDICINAL CHEMISTRY, Jun. 2007, Reviewed, No invitation

Activation of TRPA1 channel facilitates excitatory synaptic transmission in substantia gelatinosa neurons of the adult rat spinal cord
Masafumi Kosugi; Terumasa Nakatsuka; Tsugumi Fujita; Yasuo Kuroda; Eiichi Kumamoto
JOURNAL OF NEUROSCIENCE, Apr. 2007, Reviewed, No invitation

Phospholipase A2 activation enhances inhibitory synaptic transmission in the rat substantia gelatinosa
T.Liu; T.Fujita; T.Nakatsuka; E.Kumamoto
Pain Research, 2007, Not reviewed, No invitation

Proteinase-activated receptor-1 activation presynaptically enhances spontaneous excitatory synaptic transmission in adult rat substantia gelatinosa neurons
T.Fujita; T.Liu; K.Mizuta; T.Nakatsuka; E.Kumamoto
Journal of Functional Diagnosis of the Spinal Cord, 2007, Not reviewed, No invitation

The effect of TRPA1 activation on excitatory synaptic transmission in the spinal dorsal horn
M.Kosugi; T.Nakatsuka; T.Fujita; T.Aoyama; E.Kumamoto
Journal of Functional Diagnosis of the Spinal Cord, 2007, Not reviewed, No invitation

Tramadol, but not its major metabolite (mono-O-demethyl tramadol) depresses compound action potentials in frog sciatic nerves
R. Katsuki; T. Fujita; A. Koga; T. Liu; T. Nakatsuka; M. Nakashima; E. Kumamoto
BRITISH JOURNAL OF PHARMACOLOGY, Oct. 2006, Not reviewed, No invitation

Enhancement by melittin of excitatory and inhibitory synaptic transmission in adult rat substantia gelatinosa neurons
T.Liu; T.Fujita; H.-Y.Yue; A.Koga; M.Kosugi; T.Nakatsuka; E.Kumamoto
Journal of Functional Diagnosis of the Spinal Cord, 2006, Not reviewed, No invitation

Inhibition by endomorphin-1 and endomorphin-2 of excitatory transmission in adult rat substantia gelatinosa neurons
T Fujita; E Kumamoto
NEUROSCIENCE, 2006, Not reviewed, No invitation

Tramadol produces outward currents by activating mu-opioid receptors in adult rat substantia gelatinosa neurones
A Koga; T Fujita; T Totoki; E Kumamoto
BRITISH JOURNAL OF PHARMACOLOGY, Jul. 2005, Not reviewed, No invitation

Tramadol produces outward currents by activating mu-opioid receptors in adult rat substantia gelatinosa neurones
A Koga; T Fujita; T Totoki; E Kumamoto
BRITISH JOURNAL OF PHARMACOLOGY, Jul. 2005, Reviewed, No invitation

Functional role of postsynaptic dopamine receptors in substantia gelatinosa neurons of the spinal cord
T.Nakatsuka; A.Tamae; K.Koga; G.Kato; T.Fujita; H.Furue; E.Kumamoto; M.Yoshimura
Pain Research, 2005, Not reviewed, No invitation

Phospholipase A(2) activation by melittin enhances spontaneous glutamatergic excitatory transmission in rat substantia gelatinosa neurons
HY Yue; T Fujita; E Kumamoto
NEUROSCIENCE, 2005, Not reviewed, No invitation

Adenosine inhibits GABAergic and Glycinergic transmission in adult rat substantia gelatinosa neurons
K Yang; T Fujita; E Kumamoto
JOURNAL OF NEUROPHYSIOLOGY, Nov. 2004, Reviewed, No invitation

AM404 enhances the spontaneous release of L-glutamate in a manner sensitive to capsazepine in adult rat substantia gelatinosa neurones
HY Yue; T Fujita; Y Kawasaki; E Kumamoto
BRAIN RESEARCH, Aug. 2004, Reviewed, No invitation

Regulation equilibrative nucleoside transporter of adenosine outward currents in adult rat spinal dorsal horn neurons
T Liu; T Fujita; Y Kawasaki; E Kumamoto
BRAIN RESEARCH BULLETIN, Jul. 2004, Reviewed, No invitation

Enhancement of the releases of GABA and glycine during ischemia in rat spinal dorsal horn
Y Kawasaki; T Fujita; E Kumamoto
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, Apr. 2004, Reviewed, No invitation

Adenosine-induced outward currents in substantia gelatinosa neurons of the adult rat spinal cord – comparison with its presynaptic actions
T.Liu; T.Fujita; K.Yang; Y.Kawasaki; A.Koga; E.Kumamoto
Pain Research, 2004, Not reviewed, No invitation

The interaction of ATP and adenosine in spinal nociceptive transmission
NAKATSUKA T.
Pain Research, 2004, Not reviewed, No invitation

Modulation by adenosine of A delta and C primary-afferent glutamatergic transmission in adult rat substantia gelatinosa neurons
LJ Lao; Y Kawasaki; K Yang; T Fujita; E Kumamoto
NEUROSCIENCE, 2004, Not reviewed, No invitation

Alterations in primary afferent input to substantia gelatinosa of adult rat spinal cord after neonatal capsaicin treatment
K Yang; H Furue; T Fujita; E Kumamoto; M Yoshimura
JOURNAL OF NEUROSCIENCE RESEARCH, Dec. 2003, Reviewed, No invitation

Modulation of nociceptive transmission by cannahinoids in the spinal dorsal horn
KAWASAKI Y.
Pain Res., 2003, Not reviewed, No invitation

The role of deltorphin II phenylalanine reside in binding to the delta opioid receptor
T Honda; N Shirasu; Y Chuman; K Okada; T Fujita; T Nose; Y Shimohigashi
BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN, Nov. 2000, Not reviewed, No invitation

Exploration of the role of phenylalanine in the thrombin receptor tethered-ligand peptide by substitution with a series of trifluorophenylalanines
A Matsushima; T Fujita; K Okada; N Shirasu; T Nose; Y Shimohigashi
BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN, Nov. 2000, Not reviewed, No invitation

Pharmacological characterization of a novel AVP(4-9) binding site in rat hippocampus
Y Nakayama; Y Takano; Y Shimohigashi; S Tanabe; T Fujita; H Kamiya; G Tsujimoto
BRAIN RESEARCH, Mar. 2000, Not reviewed, No invitation

Synthesis of a complete set of L-difluorophenylalanines, L-(F-2)Phe, as molecular explorers for the CH/-pi interaction between peptide ligand and receptor
T Fujita; T Nose; A Matsushima; K Okada; D Asai; Y Yamauchi; N Shirasu; T Honda; D Shigehiro; Y Shimohigashi
TETRAHEDRON LETTERS, Feb. 2000, Not reviewed, No invitation

Edge-to-face CH/π interaction between ligand Phe-phenyl and receptor aromatic group in the thrombin receptor activation
A. Matsushima; T. Fujita; T. Nose; Y. Shimohigashi
Journal of Biochemistry, 2000, Not reviewed, No invitation

In vivo and in vitro evidence of blood-brain barrier transport of a novel cationic arginine-vasopressin fragment 4-9 analog
S Tanabe; Y Shimohigashi; Y Nakayama; T Makino; T Fujita; T Nose; G Tsujimoto; T Yokokura; M Naito; T Tsuruo; T Terasaki
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, Aug. 1999, Not reviewed, No invitation

A novel molecular design of thrombin receptor antagonist
T Fujita; M Nakajima; Y Inoue; T Nose; Y Shimohigashi
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, May 1999, Not reviewed, No invitation

Agonist-antagonist structure-activity relationships of thrombin receptor tethered ligand peptide
T Fujita; T Nose; M Nakajima; Y Inoue; N Nakamura; T Inoue; T Costa; Y Shimohigashi
PEPTIDE SCIENCE - PRESENT AND FUTURE, 1999, Reviewed, No invitation

Design and synthesis of para-fluorophenylalanine amide derivatives as thrombin receptor antagonists
Tsugumi Fujita; Takeru Nose; Masahide Nakajima; Yoshihisa Inoue; Tommaso Costa; Yasuyuki Shimohigashi
Journal of Biochemistry, 1999, Not reviewed, No invitation

Interaction mode of the phe-phenyl group of thrombin receptor-tethered ligand SFLLRNP in receptor activation
T Nose; T Fujita; M Nakajima; Y Inoue; T Costa; Y Shimohigashi
JOURNAL OF BIOCHEMISTRY, Aug. 1998, Not reviewed, No invitation

The role of arginine in thrombin receptor tethered-ligand peptide in intramolecular receptor binding and self-activation
T Nose; Y Satoh; T Fujita; M Ohno; M Nakajima; Y Inoue; Y Ogino; T Costa; Y Shimohigashi
BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN, Jul. 1998, Not reviewed, No invitation

Exclusive affinity-labeling of mu opioid receptors by morphiceptin analogs containing S-(3-nitro-2-pyridylthio)cysteine
S Motoyama; K Takada; T Yasunaga; T Fujita; Y Shimohigashi
BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN, Dec. 1996, Not reviewed, No invitation

Sensitivity of opioid receptor-like receptor ORL1 for chemical modification on nociceptin, a naturally occurring nociceptive peptide
Y Shimohigashi; R Hatano; T Fujita; R Nakashima; T Nose; T Sujaku; A Saigo; K Shinjo; A Nagahisa
JOURNAL OF BIOLOGICAL CHEMISTRY, Sep. 1996, Not reviewed, No invitation

Functional roles of phenylalanine-2 of thrombin receptor-tethered ligand peptide in platelet activation
T Nose; Y Shimohigashi; T Fujita; H Akikubo; T Costa; M Ohno
PEPTIDE CHEMISTRY 1995, 1996, Reviewed, No invitation

Analgesics and analgesic adjuvants inhibiting nerve conduction in the frog sciatic nerve —local anesthetics, opioids, α₂ adrenoceptor agonists, antiepileptics, antidepressants and NSAIDs
Eiichi Kumamoto; Tsugumi Fujita
PAIN RESEARCH, 20 Dec. 2019, Reviewed

Cellular mechanisms for antinociception produced by hypothalamus–derived neuropeptides in the rat spinal superficial dorsal horn —oxytocin and orexins actions
Eiichi Kumamoto; Tsugumi Fujita; Chong Wang
PAIN RESEARCH, 20 Sep. 2019, Reviewed

非ステロイド性抗炎症薬による蛙坐骨神経の複合活動電位の抑制とその化学構造
鈴木里佳; 藤田亜美; 水田恒太郎; 馬郡信弥; 王ちゅう; 楊帆; 熊本栄一
日本生理学雑誌(Web), May 2018, Not reviewed, No invitation

Modulation of TRP Activation and Nerve Conduction for Analgesia
Eiichi Kumamoto; Tsugumi Fujita; Rika Suzuki; Nobuya Magori; Chong Wang
Analgesia & Resuscitation : Current Research, 2018, Reviewed

Differential activation of TRP channels in the adult rat spinal substantia gelatinosa by stereoisomers of plant-derived chemicals
Eiichi Kumamoto; Tsugumi Fujita
Pharmaceuticals, 01 Sep. 2016, Reviewed, No invitation

Transient receptor potentialチャネル活性化による神経終末からのグルタミン酸自発放出の促進
熊本 栄一; 藤田 亜美
生物物理, May 2016, Not reviewed, No invitation

成熟ラット脊髄膠様質ニューロンの自発性興奮性シナプス伝達に及ぼすチモールの作用
徐 志昊; 蒋 昌宇; 藤田 亜美; 朱 蘭; 王 ちゅう; 熊本 栄一
脊髄機能診断学, Jan. 2016, Not reviewed, No invitation

カルボンによるTRPチャネル活性化を介したラット脊髄膠様質ニューロンの自発性興奮性シナプス伝達の促進
康 欽; 蒋 昌宇; 藤田 亜美; 朱 蘭; 熊本 栄一
脊髄機能診断学, Jan. 2016, Not reviewed, No invitation

アロマ精油成分による化学構造に依存した蛙坐骨神経の複合活動電位抑制
大坪 瀬奈; 藤田 亜美; 宮原 萌; 松下 晋大; 蒋 昌宇; 徐 志昊; 熊本 栄一
PAIN RESEARCH, Mar. 2015, Not reviewed, No invitation

成熟ラット脊髄膠様質ニューロンのオキシトシンによる膜脱分極の解析
蒋 昌宇; 藤田 亜美; 大坪 瀬奈; 松下 晋大; 徐 志昊; 熊本 栄一
脊髄機能診断学, Jan. 2015, Not reviewed, No invitation

カルバクロールによるラット脊髄膠様質ニューロンの自発性興奮性シナプス伝達促進と膜過分極
羅 清甜; 藤田 亜美; 蒋 昌宇; 大坪 瀬奈; 康 欽; 松下 晋大; 徐 志昊; 熊本 栄一
脊髄機能診断学, Jan. 2015, Not reviewed, No invitation

シネオールによるTRP活性化を介したラット脊髄膠様質の自発性グルタミン酸放出の促進
徐 年香; 蒋 昌宇; 藤田 亜美; 大坪 瀬奈; 松下 晋大; 徐 志昊; 熊本 栄一
脊髄機能診断学, Jan. 2015, Not reviewed, No invitation

ラット脊髄後角第II層ニューロンに及ぼすオキシトシンの作用 鎮痛作用機序
蒋 昌宇; 藤田 亜美; 徐 志昊; 大坪 瀬奈; 松下 晋大; 熊本 栄一
PAIN RESEARCH, Dec. 2014, Not reviewed, No invitation

インターロイキン-27ノックアウトマウスの疼痛行動解析
八坂 敏一; 笹栗 智子; 村田 祐造; 原 博満; 石川 亜佐子; 藤田 亜美; 熊本 栄一; 増子 貞彦; 平川 奈緒美; 吉田 裕樹
PAIN RESEARCH, Jun. 2014, Not reviewed, No invitation

TRP Channels Involved in Spontaneous L-Glutamate Release Enhancement in the Adult Rat Spinal Substantia Gelatinosa.
Kumamoto E; Fujita T; Jiang CY
Cells, Apr. 2014, Reviewed, No invitation

カエル坐骨神経の複合活動電位に及ぼすアロマ精油成分の抑制作用
大坪 瀬奈; 藤田 亜美; 松下 晋大; 蒋 昌宇; 熊本 栄一
PAIN RESEARCH, Mar. 2014, Not reviewed, No invitation

TRPチャネルとシナプス活動
熊本栄一; 藤田亜美; 蒋昌宇; 徐志昊; 大坪瀬奈; 松下晋大
日本生理学会誌 (WEB版), 2014, Not reviewed, Invited

Enhancement by Oxytocin of Spontaneous Inhibitory Transmission in Adult Rat Spinal Superficial Dorsal Horn Neurons
JIANG Chang-Yu; FUJITA Tsugumi; LUO Qing-Tian; KANG Qin; MATSUSHITA Akitomo; OHTSUBO Sena; KUMAMOTO Eiichi
Peptide science : proceedings of the ... Japanese Peptide Symposium, 01 Mar. 2013

カエル坐骨神経の複合活動電位に及ぼす漢方薬の作用
松下 晋大; 藤田 亜美; 水田 恒太郎; 大坪 瀬奈; 蒋 昌宇; 上村 裕平; 小杉 寿文; 熊本 栄一
PAIN RESEARCH, Mar. 2013, Not reviewed, No invitation

ラット脊髄膠様質ニューロンの自発性興奮性シナプス伝達に及ぼすピペリンとオルバニルの作用の差
楊 柳; 藤田 亜美; 蒋 昌宇; 水田 恒太郎; 井上 将成; 川崎 弘貴; 徐 年香; 松下 晋大; 柳 涛; 熊本 栄一
脊髄機能診断学, Feb. 2013, Not reviewed, No invitation

成熟ラット脊髄膠様質ニューロンに及ぼすオキシトシンの作用
蒋 昌宇; 藤田 亜美; 楊 柳; 水田 恒太郎; 井上 将成; 川崎 弘貴; 徐 年香; 松下 晋大; 柳 涛; 熊本 栄一
脊髄機能診断学, Feb. 2013, Not reviewed, No invitation

Comparison among various types of anticonvulsant in the extent of the inhibition of compound action potentials in the frog sciatic nerve
Yuhei Uemura; Tsugumi Fujita; Sena Ohtsubo; Akitomo Matsushita; Jiang Chang-Yu; Eiichi Kumamoto
JOURNAL OF PHYSIOLOGICAL SCIENCES, 2013, Not reviewed, No invitation

Oxytocin facilitates inhibitory transmission without a change in excitatory transmission in adult rat spinal substantia gelatinosa neurons
Jiang Chang-Yu; Tsugumi Fujita; Xu Nian-Xiang; Luo Qing-Tian; Kang Qin; Akitomo Matsushita; Sena Ohtsubo; Eiichi Kumamoto
JOURNAL OF PHYSIOLOGICAL SCIENCES, 2013, Not reviewed, No invitation

Aroma-oil compounds inhibit the compound action potentials of frog sciatic nerves
Sena Ohtsubo; Tsugumi Fujita; Akitomo Matsushita; Hiroki Kawasaki; Chang-Yu Jiang; Qing-Tian Luo; Qin Kang; Eiichi Kumamoto
JOURNAL OF PHYSIOLOGICAL SCIENCES, 2013, Not reviewed, No invitation

新しいベンゾジアゼピン受容体作動薬JM1232(-)は脊髄後角ニューロンの抑制性シナプス伝達を促進する
上村聡子; 藤田亜美; 八坂敏一; 蒋昌宇; 水田恒太郎; 川崎弘貴; 井上将成; 熊本栄一
日本生理学雑誌, 01 May 2012, Not reviewed, No invitation

ラット後根神経節ニューロンの活動電位のオピオイドによる抑制
水田恒太郎; 藤田亜美; 蒋昌宇; 井上将成; 上村聡子; 徐年香; 川崎弘貴; 松下晋大; 八坂敏一; 柳涛; 熊本栄一
日本生理学雑誌, 01 May 2012, Not reviewed, No invitation

成熟ラット脊髄膠様質のTRPA1活性化を介したオイゲノールによる自発性グルタミン酸放出の促進
井上将成; 藤田亜美; 水田恒太郎; 上村聡子; 蒋昌宇; 八坂敏一; 柳涛; 熊本栄一
日本生理学雑誌, 01 May 2012, Not reviewed, No invitation

蛙坐骨神経の複合活動電位に対するメントールの抑制作用
川崎弘貴; 水田恒太郎; 藤田亜美; 蒋昌宇; 上村聡子; 八坂敏一; 井上将成; 松下晋大; 熊本栄一
日本生理学雑誌, 01 May 2012, Not reviewed, No invitation

成熟ラット脊髄後角膠様質ニューロンの自発性興奮性シナプス伝達に対するピペリンとオルバニルの作用
楊柳; 藤田亜美; 蒋昌宇; 水田恒太郎; 井上将成; 上村聡子; 八坂敏一; 柳涛; 徐年香; 熊本栄一
日本生理学雑誌, 01 May 2012, Not reviewed, No invitation

Oxytocin Increases the Excitability of Spinal Superficial Dorsal Horn Neurons in Adult Male Rats
JIANG Chang-Yu; FUJITA Tsugumi; LIU Tao; MIZUTA Kotaro; YUE Hai-Yuan; KUMAMOTO Eiichi
Peptide science : proceedings of the ... Japanese Peptide Symposium, 01 Mar. 2012

メントールとその関連物質による蛙坐骨神経の複合活動電位の抑制
川崎弘貴; 水田恒太郎; 藤田亜美; JIANG Chang‐Yu; 上村聡子; 八坂敏一; 井上将成; 熊本栄一
Pain Research, 22 Jul. 2011, Not reviewed, No invitation

成熟ラット脊髄膠様質ニューロンの膜興奮性に及ぼすオキシトシンの作用
JIANG Chang‐Yu; 藤田亜美; 上村聡子; 水田恒太郎; 川崎弘貴; 八坂敏一; 井上将成; 熊本栄一
Pain Res, 22 Jul. 2011, Not reviewed, No invitation

成熟ラット脊髄膠様質ニューロンのシナプス,伝達に及ぼすイソインドリン誘導体JM1232(-)の作用
上村聡子; 藤田亜美; 八坂敏一; JIANG Chang‐Yu; 水田恒太郎; 川崎弘貴; 井上将成; 熊本栄一
Pain Res, 22 Jul. 2011, Not reviewed, No invitation

痛み伝達に関与するラット後根神経節ニューロンの活動電位に及ぼすオピオイドの抑制効果
水田恒太郎; 藤田亜美; JIANG Chang‐Yu; 井上将成; 上村聡子; 川崎弘貴; 八坂敏一; 熊本栄一
Pain Res, 22 Jul. 2011, Not reviewed, No invitation

Inhibition by Galanin of Monosynaptic Primary-Afferent Aδ-Fiber and C-Fiber Excitatory Transmission in Adult Rat Spinal Dorsal Horn Neurons
YUE Hai-Yuan; FUJITA Tsugumi; PIAO Lian-Hua; JIANG Chang-Yu; INOUE Masanari; MIZUTA Kotaro; YASAKA Toshiharu; YANG Liu; KAWASAKI Hiroki; KUMAMOTO Eiichi
Peptide science : proceedings of the ... Japanese Peptide Symposium, 01 Mar. 2011

Oxytocin produces a membrane depolarization in adult rat spinal substantia gelatinosa neurons
Chang-Yu Jiang; Tsugumi Fujita; Hai-Yuan Yue; Liu Yang; Kotaro Mizuta; Masanari Inoue; Satoko Uemura; Hiroki Kawasaki; Toshiharu Yasaka; Lian-Hua Piao; Eiichi Kumamoto
NEUROSCIENCE RESEARCH, 2011, Not reviewed, No invitation

Glutamatergic spontaneous excitatory transmission enhancement produced by eugenol is due to TRPA1 channel activation in the rat spinal dorsal horn
Masanari Inoue; Tsugumi Fujita; Lian-Hua Piao; Hai-Yuan Yue; Kotaro Mizuta; Chang-Yu Jiang; Satoko Uemura; Liu Yang; Toshiharu Yasaka; Hiroki Kawasaki; Eiichi Kumamoto
NEUROSCIENCE RESEARCH, 2011, Not reviewed, No invitation

Opioids reduce the peak amplitude of action potential in adult rat dorsal root ganglion neurons
Kotaro Mizuta; Tsugumi Fujita; Chang-Yu Jiang; Hai-Yuan Yue; Masanari Inoue; Liu Yang; Satoko Uemura; Hiroki Kawasaki; Lian-Hua Piao; Toshiharu Yasaka; Eiichi Kumamoto
NEUROSCIENCE RESEARCH, 2011, Not reviewed, No invitation

Populations of lamina II interneurons possessing C-fiber inputs in the spinal dorsal horn of adult rats which received neonatal capsaicin treatments
Toshiharu Yasaka; Ming-Zi Li; Yuzo Murata; Tsugumi Fujita; Sadahiko Masuko; Andrew Todd; Eiichi Kumamoto
NEUROSCIENCE RESEARCH, 2011, Not reviewed, No invitation

Inhibition by TRPM8 agonist menthol and its related substances with p-menthane base of compound action potentials in frog sciatic nerves
Hiroki Kawasaki; Kotaro Mizuta; Tsugumi Fujita; Masanari Inoue; Chang-Yu Jiang; Toshiharu Yasaka; Satoko Uemura; Hai-Yuan Yue; Liu Yang; Eiichi Kumamoto
NEUROSCIENCE RESEARCH, 2011, Not reviewed, No invitation

成熟ラット脊髄膠様質ニューロンにおける自発性グルタミン酸放出のジンゲロンによる促進
岳海源; 藤田亜美; 朴蓮花; 井上将成; 蒋昌宇; 水田恒太郎; 八坂敏一; 川崎弘貴; 熊本栄一
日本生理学雑誌, 01 Jan. 2011, Not reviewed, No invitation

成熟ラット脊髄膠様質ニューロンにおけるグルタミン酸作動性自発性興奮性シナプス伝達に及ぼすオイゲノールの促進作用
井上将成; 藤田亜美; 水田恒太郎; 朴蓮花; 岳海源; 八坂敏一; 熊本栄一
日本生理学雑誌, 01 Jan. 2011, Not reviewed, No invitation

ラット脊髄膠様質ニューロンにおける興奮性シナプス伝達のテトラカインによる促進作用
朴蓮花; 藤田亜美; 岳海源; 蒋昌宇; 井上将成; 八坂敏一; 水田恒太郎; 上村聡子; 楊柳; 熊本栄一
日本生理学雑誌, 01 Jan. 2011, Not reviewed, No invitation

ベンゾジアゼピン系薬物とGABAA受容体チャネル
熊本栄一; 藤田亜美
Anesthesia 21 Century, 2011, Not reviewed, No invitation

ラット脊髄膠様質ニューロンにおける興奮性シナプス伝達のオイゲノールによる促進作用
井上将成; 藤田亜美; PIAO Lian‐Hua; YUE Hai‐Yuan; 水田恒太郎; 青山貴博; 八坂敏一; 熊本栄一
Pain Research, 02 Jul. 2010, Not reviewed, No invitation

ラット脊髄膠様質ニューロンの自発性興奮性シナプス伝達に及ぼすジンゲロンの作用
YUE Hai‐Yuan; 藤田亜美; PIAO Lian‐Hua; 井上将成; 水田恒太郎; 八坂敏一; 上村聡子; JIANG Chang‐Yu; 熊本栄一
Pain Research, 02 Jul. 2010, Not reviewed, No invitation

成熟ラット脊髄膠様質の興奮性シナプス伝達に及ぼす局所麻酔薬の作用
PIAO Lian‐Hua; 藤田亜美; YUE Hai‐Yuan; 井上将成; 八坂敏一; 水田恒太郎; JIANG Chang‐Yu; 熊本栄一
Pain Research, 02 Jul. 2010, Not reviewed, No invitation

アドレナリンα₂受容体作動薬のデクスメデトミジンによる蛙坐骨神経複合活動電位抑制
小杉寿文; 水田恒太郎; 藤田亜美; 上村聡子; 八坂敏一; 熊本栄一
日本生理学雑誌, 01 Feb. 2010, Not reviewed, No invitation

リドカインによるラット脊髄膠様質のTRPA1活性化を介したグルタミン酸放出促進
朴蓮花; 藤田亜美; 岳海源; 井上将成; 水田恒太郎; 八坂敏一; 熊本栄一
日本生理学雑誌, 01 Feb. 2010, Not reviewed, No invitation

ガラニンはラット脊髄膠様質ニューロンにおける後根刺激誘起の単シナプス性興奮性シナプス伝達を抑制する
岳海源; 藤田亜美; 朴蓮花; 水田恒太郎; 八坂敏一; 熊本栄一
日本生理学雑誌, 01 Feb. 2010, Not reviewed, No invitation

Effect of eugenol on glutamatergic spontaneous excitatory synaptic transmission in adult rat spinal dorsal horn neurons
Masanari Inoue; Tsugumi Fujita; Hai-Yuan Yue; Lian-Hua Piao; Kotaro Mizuta; Toshiharu Yasaka; Daisuke Tomohiro; Eiichi Kumamoto
NEUROSCIENCE RESEARCH, 2010, Not reviewed, No invitation

Effect of zingerone on spontaneous excitatory synaptic transmission in adult rat spinal substantia gelatinosa neurons
Hai-Yuan Yue; Tsugumi Fujita; Lian-Hua Piao; Masanari Inoue; Kotaro Mizuta; Chang-Yu Jiang; Satoko Uemura; Eiichi Kumamoto
NEUROSCIENCE RESEARCH, 2010, Not reviewed, No invitation

In vivo patch-clamp analysis of the actions of dopaminergic nervous system in substantia gelatinosa neurons of the rat spinal cord
Wataru Taniguchi; Terumasa Nakatsuka; Nobuyuki Miyazaki; Tadakazu Abe; Noboru Takiguchi; Yasuhiko Kawasaki; Daisuke Takeda; Tsugumi Fujita; Eiichi Kumamoto; Munehito Yoshida
NEUROSCIENCE RESEARCH, 2010, Not reviewed, No invitation

Electrophysiological and pharmacological features of morphologically classified inhibitory and excitatory interneurons in the adult rat spinal dorsal horn
Toshiharu Yasaka; Sheena Y. X. Tiong; David Hughes; John S. Riddell; Andrew J. Todd; Tsugumi Fujita; Elichi Kumamoto
JOURNAL OF PHYSIOLOGICAL SCIENCES, 2010, Not reviewed, No invitation

Effects of local anesthetics on spontaneous excitatory synaptic transmission in adult rat spinal substantia gelatinosa neurons
Lian-Hua Piao; Tsugumi Fujita; Hai-Yuan Yue; Chang-Yu Jiang; Masanari Inoue; Kotaro Mizuta; Satoko Uemura; Eiichi Kumamoto
NEUROSCIENCE RESEARCH, 2010, Not reviewed, No invitation

Zingerone facilitates spontaneous L-glutamate release in spinal substantia gelatinosa neurons in a manner independent of TRPV1 activation
Hai-Yuan Yue; Tsugumi Fujita; Lian-Hua Piao; Masanari Inoue; Kotaro Mizuta; Chang-Yu Jiang; Toshiharu Yasaka; Eiichi Kumamoto
JOURNAL OF PHYSIOLOGICAL SCIENCES, 2010, Not reviewed, No invitation

Nerve conduction block by alpha(2) adrenoceptor agonists in frog sciatic nerves
Kotaro Mizuta; Toshifumi Kosugi; Tsugumi Fujita; Hai-Yuan Yue; Lian-Hua Piao; Yuhei Uemura; Masanari Inoue; Toshiharu Yasaka; Eiichi Kumamoto
NEUROSCIENCE RESEARCH, 2010, Not reviewed, No invitation

Bisphenol A inhibits compound action potentials in frog sciatic nerves
Kotaro Mizuta; Tsugumi Fujita; Yamagata Hiroki; Markus Lommi; Toshiharu Yasaka; Elichi Kumamoto
JOURNAL OF PHYSIOLOGICAL SCIENCES, 2010, Not reviewed, No invitation

The effects of bisphenol A on compound action potentials in frog sciatic nerves
Tsugumi Fujita; Kotaro Mizuta; Hai-Yuan Yue; Lian-Hua Piao; Chang-Yu Jiang; Hiroki Yamagata; Toshiharu Yasaka; Eiichi Kumamoto
NEUROSCIENCE RESEARCH, 2010, Not reviewed, No invitation

Activation of P2X and P2Y receptors enhances excitatory transmission in rat spinal ventral horn neurons
Tsugumi Fujita; Takahiro Aoyama; Shugo Koga; Terumasa Nakatsuka; Satoko Uemura; Toshiharu Yasaka; Eiichi Kumamoto
JOURNAL OF PHYSIOLOGICAL SCIENCES, 2010, Not reviewed, No invitation

Eugenol enhances glutamatergic spontaneous excitatory transmission in adult rat spinal substantia gelatinosa neurons
Masanari Inoue; Tsugumi Fujita; Hai-Yuan Yue; Lian-Hua Piao; Kotaro Mizuta; Daisuke Tomohiro; Takahiro Aoyama; Toshiharu Yasaka; Eiichi Kumamoto
JOURNAL OF PHYSIOLOGICAL SCIENCES, 2010, Not reviewed, No invitation

Spontaneous L-glutamate release increase produced by local anesthetics-induced TRP activation in the rat spinal substantia gelatinosa
Lian-Hua Piao; Tsugumi Fujita; Hai-Yuan Yue; Chang-Yu Jiang; Masanari Inoue; Kotaro Mizuta; Toshiharu Yasaka; Eiichi Kumamoto
JOURNAL OF PHYSIOLOGICAL SCIENCES, 2010, Not reviewed, No invitation

成熟ラット脊髄膠様質におけるTRPA1チャネルのリドカインによる活性化
PIAO Lian‐Hua; 藤田亜美; YUE Hai‐Yuan; 水田恒太郎; 井上将成; 中塚映政; 熊本栄一
Pain Research, 17 Jul. 2009, Not reviewed, No invitation

バニリル基を持つカプサイシンやその類似物資によるカエル坐骨神経の複合活動電位抑制
水田恒太郎; 藤田亜美; 上村裕平; 中塚映政; 熊本栄一
Pain Research, 17 Jul. 2009, Not reviewed, No invitation

Action of Galanin on Synaptic Transmission in Substantia Gelatinosa Neurons of the Adult Rat Spinal Cord
YUE Hai-Yuan; FUJITA Tsugumi; LIU Tao; PIAO Lian-Hua; MIZUTA Kotaro; NAKATSUKA Terumasa; KUMAMOTO Eiichi
Peptide science : proceedings of the ... Japanese Peptide Symposium, 01 Mar. 2009

Glutamatergic Excitatory Transmission in Adult Rat Substantia Gelatinosa Neurons Is Enhanced More Effectively by PAR-1 than PAR-2 and PAR-4 Activating Peptides
FUJITA Tsugumi; LIU Tao; AOYAMA Takahiro; TOMOHIRO Daisuke; NAKATSUKA Terumasa; KUMAMOTO Eiichi
Peptide science : proceedings of the ... Japanese Peptide Symposium, 01 Mar. 2009

ラット脊髄後角膠様質ニューロンの自発性興奮性シナプス伝達に対するレシニフェラトキシンの作用
蒋昌宇; 藤田亜美; 柳涛; 岳海源; 朴蓮花; 水田恒太郎; 友廣大輔; 青山貴博; 中塚映政; 熊本栄一
日本生理学雑誌, 01 Mar. 2009, Not reviewed, No invitation

カエル坐骨神経の複合活動電位に及ぼすカプサイシンとその関連物質の抑制効果
友廣大輔; 水田恒太郎; 藤田亜美; 柳涛; 岳海源; 朴蓮花; 青山貴博; 中塚映政; 熊本栄一
日本生理学雑誌, 01 Mar. 2009, Not reviewed, No invitation

ラット脊髄後角膠様質ニューロンの膜興奮性に及ぼすガラニンの二相性作用
岳海源; 藤田亜美; 柳涛; 朴蓮花; 水田恒太郎; 友廣大輔; 青山貴博; 中塚映政; 熊本栄一
日本生理学雑誌, 01 Mar. 2009, Not reviewed, No invitation

Monosynaptically-evoked glutamatergic transmission though primary afferents is not enhanced by PAR-1 activation in the rat substantia gelatinosa
Tsugumi Fujita; Hai-Yuan Yue; Takahiro Aoyama; Eiichi Kumamoto
NEUROSCIENCE RESEARCH, 2009, Not reviewed, No invitation

ACTIVATION OF TRP CHANNELS BY LIDOCAINE IN SUBSTANTIA GELATINOSA NEURONS OF THE ADULT RAT SPINAL CORD
Lian-Hua Piao; Tsugumi Fujita; Chang-Yu Jiang; Tao Liu; Hai-Yuan Yue; Masanari Inoue; Satoko Uemura; Terumasa Nakatsuka; Eiichi Kumamoto
JOURNAL OF PHYSIOLOGICAL SCIENCES, 2009, Not reviewed, No invitation

Galanin inhibits primary-afferent evoked glutamatergic excitatory transmission in rat substantial gelatinosa neurons
Hai-Yuan Yue; Tsugumi Fujita; Lian-Hua Piao; Kotaro Mizuta; Satoko Uemura; Eiichi Kumamoto
NEUROSCIENCE RESEARCH, 2009, Not reviewed, No invitation

ENHANCEMENT BY RESINIFERATOXIN OF GLUTAMATERGIC EXCITATORY TRANSMISSION IN ADULT RAT SUBSTANTIA GELATINOSA NEURONS
Chang-Yu Jiang; Tsugumi Fujita; Tao Liu; Hai-Yuan Yue; Lian-Hua Piao; Masanari Inoue; Kotaro Mizuta; Terumasa Nakatsuka; Eiichi Kumamoto
JOURNAL OF PHYSIOLOGICAL SCIENCES, 2009, Not reviewed, No invitation

ENHANCEMENT BY MELITTIN OF EACH OF GABAERGIC AND GLYCINERGIC TRANSMISSION IN RAT SUBSTANTIA GELATINOSA NEURONS BY A DIFFERENT MECHANISM
Tao Liu; Tsugumi Fujita; Hai-Yuan Yue; Lian-Hua Piao; Kotaro Mizuta; Takahiro Aoyama; Terumasa Nakatsuka; Eiichi Kumamoto
JOURNAL OF PHYSIOLOGICAL SCIENCES, 2009, Not reviewed, No invitation

PRE- AND POSTSYNAPTIC EFFECTS OF GALANIN ON EXCITATORY SYNAPTIC TRANSMISSION IN RAT SUBSTANTIA GELATINOSA NEURONS
Hai-Yuan Yue; Tsugumi Fujita; Tao Liu; Lian-Hua Piao; Kotaro Mizuta; Terumasa Nakatsuka; Eiichi Kumamoto
JOURNAL OF PHYSIOLOGICAL SCIENCES, 2009, Not reviewed, No invitation

INHIBITION BY CAPSAICIN OF COMPOUND ACTION POTENTIAL IN FROG SCIATIC NERVES WITHOUT TRPV1 ACTIVATION
Kotaro Mizuta; Daisuke Tomohiro; Tsugumi Fujita; Yukiko Nishikubo; Masanari Inoue; Terumasa Nakatsuka; Eiichi Kumamoto
JOURNAL OF PHYSIOLOGICAL SCIENCES, 2009, Not reviewed, No invitation

ACTIVATION OF PROTEINASE-ACTIVATED RECEPTOR-1 ENHANCES EXCITATORY TRANSMISSION IN THE RAT SPINAL DORSAL HORN
Tsugumi Fujita; Tao Liu; Takahiro Aoyama; Terumasa Nakatsuka; Eiichi Kumamoto
JOURNAL OF PHYSIOLOGICAL SCIENCES, 2009, Not reviewed, No invitation

INHIBITION BY DEXMEDETOMIDINE AND VARIOUS LOCAL ANESTHETICS OF COMPOUND ACTION POTENTIALS IN FROG SCIATIC NERVES
Toshifumi Kosugi; Kotaro Mizuta; Daisuke Tomohiro; Tsugumi Fujita; Ryo Katsuki; Satoko Uemura; Terumasa Nakatsuka; Mikio Nakashima; Eiichi Kumamoto
JOURNAL OF PHYSIOLOGICAL SCIENCES, 2009, Not reviewed, No invitation

PRE- AND POSTSYNAPTIC EXCITATORY TRANSMISSION ENHANCEMENT BY PURINERGIC RECEPTOR ACTIVATION IN RAT SPINAL MOTONEURONS
Takahiro Aoyama; Terumasa Nakatsuka; Yasuhiko Kawasaki; Wataru Taniguchi; Tsugumi Fujita; Eiichi Kumamoto
JOURNAL OF PHYSIOLOGICAL SCIENCES, 2009, Not reviewed, No invitation

IN VIVO PATCH-CLAMP ANALYSIS OF THE ACTIONS OF DOPAMINE ON SYNAPTIC TRANSMISSION IN SUBSTANTIA GELATINOSA NEURONS OF THE RAT SPINAL CORD
Wataru Taniguchi; Terumasa Nakatsuka; Takahiro Aoyama; Yasuhiko Kawasaki; Tsugumi Fujita; Munehito Yoshida; Eiichi Kumamoto
JOURNAL OF PHYSIOLOGICAL SCIENCES, 2009, Not reviewed, No invitation

Activation by local anesthetics of TRP channels in the adult rat spinal dorsal horn
Lian-Hua Piao; Tsugumi Fujita; Hai-Yuan Yue; Chang-Yu Jiang; Masanari Inoue; Eiichi Kumamoto
NEUROSCIENCE RESEARCH, 2009, Not reviewed, No invitation

ラット脊髄膠様質の抑制性シナプス伝達のホスホリパーゼA₂活性化による促進の機序
LIU Tao; 藤田亜美; YUE Hai‐Yuan; PIAO Lian‐Hua; 水田恒太郎; 青山貴博; 中塚映政; 熊本栄一
Pain Research, 19 Jul. 2008, Not reviewed, No invitation

カエル坐骨神経の複合活動電位に及ぼすデクスメデトミジンの作用
小杉寿文; 水田恒太郎; 藤田亜美; 香月亮; 中塚映政; 中島幹夫; 熊本栄一
Pain Res, 19 Jul. 2008, Not reviewed, No invitation

ラット脊髄後角ニューロンの興奮性シナプス伝達に対するガラニンのシナプス前性および後性作用
YUE Hai‐Yuan; 藤田亜美; LIU Tao; PIAO Lian‐Hua; 青山貴博; 水田恒太郎; 中塚映政; 熊本栄一
Pain Research, 19 Jul. 2008, Not reviewed, No invitation

オピオイドによるカエル坐骨神経の複合活動電位抑制と構造活性連関
水田恒太郎; 藤田亜美; 香月亮; 柳涛; 朴蓮花; 岳海源; 友廣大輔; 中塚映政; 熊本栄一
日本生理学雑誌, 01 Feb. 2008, Not reviewed, No invitation

ラット脊髄後角のGABAとグリシンによる抑制性シナプス伝達のメリチンによる促進
柳涛; 藤田亜美; 岳海源; 朴蓮花; 水田恒太郎; 中塚映政; 熊本栄一
日本生理学雑誌, 01 Feb. 2008, Not reviewed, No invitation

トラマドールとその代謝物mono‐O‐demethyl‐tramadol(M1)のカエル坐骨神経複合活動電位に対する作用
香月亮; 藤田亜美; 水田恒太郎; 小杉寿文; 柳涛; 中塚映政; 熊本栄一
日本生理学雑誌, 01 Feb. 2008, Not reviewed, No invitation

Capsaicin and its analogs inhibit compound action potentials in frog sciatic nerves
Daisuke Tomohiro; Kotarou Mizuta; Tsugumi Fujita; Terumasa Nakatsuka; Eiichi Kumamoto
NEUROSCIENCE RESEARCH, 2008, Not reviewed, No invitation

Effect of galanin on excitatory synaptic transmission in rat substantia gelatinosa neurons
Hai-Yuan Yue; Tsugumi Fujita; Tao Liu; Chang-Yu Jiang; Kotaro Mizuta; Terumasa Nakatsuka; Eiichi Kumamoto
NEUROSCIENCE RESEARCH, 2008, Not reviewed, No invitation

Lidocaine activates TRP channels in substantia gelatinosa neurons of the rat spinal cord
Lian-Hua Piao; Chang-Yu Jiang; Tsugumi Fujita; Tao Liu; Hai-Yuan Yue; Kotarou Mizuta; Takahiro Aoyama; Terumasa Nakatsuka; Eiichi Kumamoto
NEUROSCIENCE RESEARCH, 2008, Not reviewed, No invitation

PAR-1 activating proteases as well as peptides presynaptically enhance excitatory transmission in rat substantia gelatinosa neurons
Tsugumi Fujita; Tao Liu; Takahiro Aoyama; Terumasa Nakatsuka; Eiichi Kumamoto
NEUROSCIENCE RESEARCH, 2008, Not reviewed, No invitation

Activation of GIRK channels in the spinal dorsal horn: A possible involvement of endogenous somatostatin
Terumasa Nakatsuka; Tsugumi Fujita; Takahiro Aoyama; Wataru Taniguchi; Eiichi Kumamoto
NEUROSCIENCE RESEARCH, 2008, Not reviewed, No invitation

Facilitation of excitatory synaptic transmission through activation of purinergic receptors in spinal motoneurons
Takahiro Aoyama; Terumasa Nakatsuka; Tsugumi Fujita; Eiichi Kumamoto
NEUROSCIENCE RESEARCH, 2008, Not reviewed, No invitation

Mechanisms for the enhancement of inhibitory transmission by phospholipase A(2) activation in the spinal dorsal horn
Tao Liu; Tsugumi Fujita; Hai-Yuan Yue; Terumasa Nakatsuka; Eiichi Kumamoto
NEUROSCIENCE RESEARCH, 2008, Not reviewed, No invitation

Dexmedetomidine inhibits compound action potentials in frog sciatic nerves
Toshifumi Kosugi; Kotaro Mizuta; Tsugumi Fujita; Ryo Katsuki; Daisuke Tomohiro; Terurnasa Nakatsuka; Eiichi Kumamoto
NEUROSCIENCE RESEARCH, 2008, Not reviewed, No invitation

蛙坐骨神経の複合活動電位に及ぼすオピオイドの抑制効果
水田恒太郎; 藤田亜美; 香月亮; LIU Tao; PIAO Lian‐Hua; YUE Hai‐Yuan; 中塚映政; 熊本栄一
Pain Res, 07 Jul. 2007, Not reviewed, No invitation

Phospholipase A_2 Activation by Melittin Enhances Glycinergic Spontaneous Inhibitory Transmission in Adult Rat Substantia Gelatinosa Neurons
LIU Tao; FUJITA Tsugumi; NAKATSUKA Terumasa; KUMAMOTO Eiichi
Peptide science : proceedings of the ... Japanese Peptide Symposium, 01 Mar. 2007

Proteinase-Activated Receptor-1 Agonist Peptides Presynaptically Enhance Nociceptive Transmission in the Adult Rat Spinal Cord
FUJITA Tsugumi; NAKATSUKA Terumasa; LIU Tao; KUMAMOTO Eiichi
Peptide science : proceedings of the ... Japanese Peptide Symposium, 01 Mar. 2007

成熟ラット脊髄後角のホスホリパーゼA₂活性化による抑制性シナプス伝達の促進
柳涛; 藤田亜美; 岳海源; 水田恒太郎; 中塚映政; 熊本栄一
日本生理学雑誌, 01 Feb. 2007, Not reviewed, No invitation

Enhancement by PAR-1 activation of glutamatergic excitatory transmission in adult rat substantia gelatinosa neurons
Tsugumi Fujita; Tao Liu; Terumasa Nakatsuka; Eiichi Kumamoto
NEUROSCIENCE RESEARCH, 2007, Not reviewed, No invitation

Inhibition by opioids of compound action potentials in frog sciatic nerves
Kotaro Mizuta; Tsugumi Fujita; Ryo Katsuki; Tao Liu; Lian-Hua Piao; Hai-Yuan Yue; Terumasa Nakatsuka; Eiichi Kumamoto
NEUROSCIENCE RESEARCH, 2007, Not reviewed, No invitation

Enhancement by phospholipase A(2) activation of glycinergic and GABAergic inhibitory transmission in rat substantia gelatinosa neurons
Tao Liu; Tsugumi Fujita; Hai-Yuan Yue; Kotaro Mizuta; Lian-Hua Piao; Terumasa Nakatsuka; Eiichi Kumamoto
NEUROSCIENCE RESEARCH, 2007, Not reviewed, No invitation

Presynaptic TRPA1 activation enhances glutamate release onto substantia gelatinosa neurons of the adult rat spinal cord
Masafumi Kosugi; Terumasa Nakatsuka; Tsugumi Fujita; Takahiro Aoyama; Eiichi Kumamoto
NEUROSCIENCE RESEARCH, 2007, Not reviewed, No invitation

Tramadol produces nerve conduction block in a manner independent of opioid receptor activation and monoamine uptake inhibition
Ryo Katsuki; Tsugumi Fujita; Kotaro Mizuta; Tao Liu; Terumasa Nakatsuka; Eiichi Kumamoto
NEUROSCIENCE RESEARCH, 2007, Not reviewed, No invitation

Enhancement by Bee Venom Melittin of Spontaneous GABAergic and Glycinergic Inhibitory Transmission in Substantia Gelatinosa Neurons of the Adult Rat Spinal Cord
LIU Tao; FUJITA Tsugumi; KOGA Akiko; NAKATSUKA Terumasa; KUMAMOTO Eiichi
Peptide science : proceedings of the ... Japanese Peptide Symposium, 01 Mar. 2006

Role of Proteinase-Activated Receptor Agonist Peptides in Regulating Nociceptive Transmission to Substantia Gelatinosa Neurons in the Adult Rat Spinal Cord
FUJITA Tsugumi; NAKATSUKA Terumasa; KOGA Akiko; LIU Tao; KUMAMOTO Eiichi
Peptide science : proceedings of the ... Japanese Peptide Symposium, 01 Mar. 2006

Effect of tramadol metabolite M1 on glutamatergic excitatory transmission in rat spinal dorsal horn neurons
Akiko Koga; Tsugumi Fujita; Tao Liu; Terumasa Nakatsuka; Eiichi Kumamoto
NEUROSCIENCE RESEARCH, 2006, Not reviewed, No invitation

Presynaptic P2Y(1) receptor-mediated enhancement of inhibitory synaptic transmission in the rat spinal dorsal horn
Terumasa Nakatsuka; Shugo Koga; Tsugumi Fujita; Tao Liu; Masafumi Kosugi; Eiichi Kumamoto
NEUROSCIENCE RESEARCH, 2006, Not reviewed, No invitation

Presynaptic enhancement by proteinase-activated receptor-1 agonist peptide of glutamatergic excitatory transmission in rat substantia gelatinosa neurons
Tsugumi Fujita; Terumasa Nakatsuka; Akiko Koga; Tao Liu; Masafumi Kosugi; Eiichi Kumamoto
NEUROSCIENCE RESEARCH, 2006, Not reviewed, No invitation

Enhancement by melittin of glycinergic transmission in adult rat substantia gelatinosa neurons
Tao Liu; Tsugumi Fujita; Akiko Koga; Masafumi Kosugi; Terumasa Nakatsuka; Eiichi Kumamoto
NEUROSCIENCE RESEARCH, 2006, Not reviewed, No invitation

Direct excitation of rat spinal ventral horn neurons by extracellular ATP
Shugo Koga; Terumasa Nakatsuka; Tsugumi Fujita; Tao Liu; Masafumi Kosugi; Eiichi Kumamoto
NEUROSCIENCE RESEARCH, 2006, Not reviewed, No invitation

Modulation by Endomorphins of Nociceptive Transmission in Rat Spinal Dorsal Horn Neurons
FUJITA Tsugumi; KAWASAKI Yasuhiko; KOGA Akiko; NAKATSUKA Terumasa; KUMAMOTO Eiichi
Peptide Science, 01 Mar. 2005

Bee Venom Peptide Melittin Enhances Spontaneous Glutamatergic Excitatory Transmission in the Rat Spinal Dorsal Horn
YUE Hai-Yuan; FUJITA Tsugumi; KOGA Akiko; KAWASAKI Yasuhiko; NAKATSUKA Terumasa; KUMAMOTO Eiichi
Peptide science : proceedings of the ... Japanese Peptide Symposium, 01 Mar. 2005

Substance P Actions on Synaptic Transmission in the Rat Spinal Dorsal Horn
NAKATSUKA Terumasa; SONOBE Hideki; TAKEDA Daisuke; KOGA Akiko; FUJITA Tsugumi; KUMAMOTO Eiichi
Peptide science : proceedings of the ... Japanese Peptide Symposium, 01 Mar. 2005

H.⇔.F相互置換ベンゼン環の機能構造探索子―血小板凝集のトロンビン受容体の機能構造構築の解析―
松島綾美; 藤田亜美; 浅井大輔; 野瀬健; 下東康幸
万有生命科学振興国際交流財団福岡シンポジウム, 14 May 2004, Not reviewed, No invitation

H→F displacement on the Phe-phenyl benzene ring in the thrombin receptor-tethered ligand peptide for elucidation of the receptor activation mechanism
Matsushima, A; Fujita, T; Asai, D; Shimohigashi, Y
Proceedings of the 4th International Symposium on Peptide and Protein Materials, 2004, Not reviewed, Invited

The Attempt to Identify the Binding Sites of Nociceptin Antagonist Ac-RYYRIK-NH_2 in ORL1 Receptor
KAWANO Michiaki; OKADA Kazushi; KIM Young Hwa; HONDA Takeshi; FUJITA Tsugumi; CHUMAN Yoshiro; NOSE Takeru; COSTA Tommaso; SHIMOHIGASHI Yasuyuki
Peptide science : proceedings of the ... Japanese Peptide Symposium, 01 Feb. 2003

Identification of Receptor Residues Functioning for Activation of ORL1 Nociceptin Receptor by Site-directed Mutageneses
OKADA Kazushi; KAWANO Michiaki; ISOZAKI Kaname; CHUMAN Yoshiro; FUJITA Tsugumi; NOSE Takeru; COSTA Tommaso; SHIMOHIGASHI Yasuyuki
Peptide science : proceedings of the ... Japanese Peptide Symposium, 01 Feb. 2003

ORL1受容体変異導入によるノシセプチンのスーパーアゴニスト・[Arg‐Lys^14‐15]ノシセプチンの高活性化の解析
岡田一志; 河野道昭; 中馬吉郎; 藤田亜美; 野瀬健; COSTA T; 下東康幸
生化学, 25 Aug. 2002, Not reviewed, No invitation

ノシセプチンアンタゴニストAc‐RYYRIK‐NH₂のORL1受容体結合部位の探索
河野道昭; 岡田一志; 金永和; 本田健; 藤田亜美; 中馬吉郎; 野瀬健; COSTA T; 下東康幸
生化学, 25 Aug. 2002, Not reviewed, No invitation

Receptor Binding Site for the Phe-2-Phenyl Group of Thrombin Receptor-Tethered Ligand Peptide : Analyses by Ala/Tyr Mutant Receptors
FUJITA Tsugumi; FUKAHORI Hidehiko; TOKUNAGA Takatoshi; CHUMAN Yoshiro; RIITANO Daniela; NOSE Takeru; COSTA Tommaso; SHIMOHIGASHI Yasuyuki
Peptide science : proceedings of the ... Japanese Peptide Symposium, 01 Mar. 2002

Characteristic Intra- and Intermolecular Interactions of Dipeptide-Chymotrypsin Complex as Specific Structural Essentials for Enzyme Inhibition
KOMADA Akira; YAMAUCHI Yasuko; IKESUE Koichi; FUJITA Tsugumi; NOSE Takeru; SAKAGUCHI Kazuyasu; SHIMOHIGASHI Yasuyuki
Peptide science : proceedings of the ... Japanese Peptide Symposium, 01 Mar. 2002

Identification of Receptor Binding Site of Nociceptin-14-15, the Residues for High Receptor Potentiation
OKADA Kazushi; CHUMAN Yoshiro; FUJITA Tsugumi; KAWANO Michiaki; NOSE Takeru; COSTA Tommaso; SHIMOHIGASHI Yasuyuki
Peptide science : proceedings of the ... Japanese Peptide Symposium, 01 Mar. 2002

キモトリプシン活性中心His57へのスタッキングによる阻害機構
駒田彰; 前田衣織; 山内泰子; 藤田亜美; 野瀬健; 下東康幸
生化学, 25 Nov. 2001, Not reviewed, No invitation

トロンビン受容体(PAR1)のリガンド結合構造の解析
野瀬健; 藤田亜美; COSTA T; 下東康幸
生化学, 25 Aug. 2001, Not reviewed, No invitation

ノシセプチン1位および4位への(F5)Phe同時置換による協同的アンタゴニスト活性の発現
岡田一志; 藤田亜美; 本田健; 河野道昭; 野瀬健; COSTA T; 下東康幸
生化学, 25 Aug. 2001, Not reviewed, No invitation

ジペプチドH‐D‐Leu‐Phe‐NH‐CH₂C₆H₄(p‐F)のキモトリプシン阻害構造要因
駒田彰; 山内泰子; 池末公一; 藤田亜美; 野瀬健; 坂口和靖; 下東康幸
生化学, 25 Aug. 2001, Not reviewed, No invitation

鎮痛ペプチド・エンドモルフィン2Phe‐Phe残基の(F₅)Phe‐(F₅)Pheジペプチド置換による生物活性の変化
本田健; 岡田一志; 藤田亜美; 野瀬健; 坂口和靖; COSTA T; 下東康幸
生化学, 25 Aug. 2001, Not reviewed, No invitation

血小板凝集におけるトロンビン受容体内蔵リガンドSFLLRNPの含ハロゲン誘導体の高活性
藤田亜美; 井上尚子; 松島綾美; 野瀬健; COSTA T; 下東康幸
生化学, 25 Apr. 2001, Not reviewed, No invitation

鎮痛ペプチド・エンドモルフィンの3位および4位フェニルアラニンのμ型オビオイド受容体への結合特性
本田健; 重弘大樹; 岡田一志; 白須直人; 中馬吉郎; 藤田亜美; 野瀬健; 坂口和靖; 下東康幸
生化学, 25 Apr. 2001, Not reviewed, No invitation

Importance of the Hydrophobicity Interaction and .PI.-.PI. Stacking Interaction in Chymotrypsin Inhibition Induced by Dipeptide D-Leu-Phe Benzylamide.
駒田彰; 藤田亜美; 野瀬健; 坂口和靖; 下東康幸
日本化学会講演予稿集, 15 Mar. 2001, Not reviewed, No invitation

Activity Enhancement by Introduction of Two Different Halogen Atoms into Phe-2-phenyl Group of Thrombin Receptor Tethered-Ligand Analogs
FUJITA Tsugumi; INOUE Naoko; MATSUSHIMA Ayami; NOSE Takeru; COSTA Tommaso; SHIMOHIGASHI Yasuyuki
Peptide science : proceedings of the ... Japanese Peptide Symposium, 01 Mar. 2001

Synergistic Potentiation of Nociceptin by Simultaneous Incorporation of Basic Amino Acids at the Consecutive Positions 14-15
OKADA Kazushi; CHUMAN Yoshiro; NAKASHIMA Rie; FUJITA Tsugumi; NOSE Takeru; COSTA Tommaso; SHIMOHIGASHI Yasuyuki
Peptide science : proceedings of the ... Japanese Peptide Symposium, 01 Mar. 2001

Differential Receptor Binding Characteristics of the Phenylalanine Residues at Positions 3-4 of Endomorphin-2
HONDA Takeshi; SHIGEHIRO Daiki; OKADA Kazushi; SHIRASU Naoto; CHUMAN Yoshiro; FUJITA Tsugumi; NOSE Takeru; SAKAGUCHI Kazuyasu; SHIMOHIGASHI Yasuyuki
Peptide science : proceedings of the ... Japanese Peptide Symposium, 01 Mar. 2001

とう痛ペプチド・ノシセプチンの高活性化とその構造要因
岡田一志; 中馬吉郎; 藤田亜美; 中島理恵; 野瀬健; COSTA T; 下東康幸
生化学, 25 Aug. 2000, Not reviewed, No invitation

含ハロゲンフェニルアラニンを導入したトロンビン受容体内蔵リガンドアナログの高活性化
藤田亜美; 井上尚子; 松島綾美; 野瀬健; COSTA T; 下東康幸
生化学, 25 Aug. 2000, Not reviewed, No invitation

オピオイドペプチド・エンドモルフィンにおけるフェニルアラニン2残基の受容体結合特性
本田健; 重弘大樹; 岡田一志; 白須直人; 中馬吉郎; 藤田亜美; 野瀬健; 坂口和靖; 下東康幸
生化学, 25 Aug. 2000, Not reviewed, No invitation

トロンビン受容体内臓リガンド2位Phe‐フェニル基のメタ位置換体のアゴニスト活性
井上尚子; 松島綾美; 藤田亜美; 野瀬健; 下東康幸
化学関連支部合同九州大会講演予稿集, 18 Jul. 2000, Not reviewed, No invitation

トロンビン受容体における含フッ素フェニルアラニンによるリガンド‐受容体相互作用様式の解析
藤田亜美; 松島綾美; 野瀬健; 栗林太; 下東康幸
生化学, 25 Mar. 2000, Not reviewed, No invitation

Chemical Syntheses of Phenylalanine Derivatives Containing Halogenated Benzene Ring as Structural Explorers for Elucidation of Molecular Mechanisms of Receptor Interacions
MATSUSHIMA Ayami; FUJITA Tsugumi; OKADA Kazushi; YAMAUCHI Yasuko; NOSE Takeru; SHIMOHIGASHI Yasuyuki
Peptide science : proceedings of the ... Japanese Peptide Symposium, 01 Mar. 2000

Highly Potent Peptide Ligands for Thrombin Receptor
FUJITA Tsugumi; NOSE Takeru; MATSUSHIMA Ayami; COSTA Tommaso; SHIMOHIGASHI Yasuyuki
Peptide science : proceedings of the ... Japanese Peptide Symposium, 01 Mar. 2000

The Mode of Molecular Interation of Phe-3 of Deltorphin II and Endomorphin 2 in Opioid Receptor Binding
HONDA Takeshi; SHIGEHIRO Daiki; SHIRASU Naoto; CHUMAN Yoshiro; FUJITA Tsugumi; NOSE Takeru; SHIMOHIGASHI Yasuyuki
Peptide science : proceedings of the ... Japanese Peptide Symposium, 01 Mar. 2000

Receptor Interaction Mode of the Phe-phenyl Group of Opioid Peptides
SHIRASU Naoto; OKADA Kazushi; CHUMAN Yoshiro; FUJITA Tsugumi; HONDA Takeshi; SHIGEHIRO Daiki; NOSE Takeru; SHIMOHIGASHI Yasuyuki
Peptide science : proceedings of the ... Japanese Peptide Symposium, 01 Mar. 2000

フッ素3置換フェニルアラニン含有トロンビン受容体内蔵リガンドの受容体活性化における構造活性相関
松島綾美; 藤田亜美; 中馬吉郎; 野瀬健; COSTA T; 下東康幸
化学関連支部合同九州大会講演予稿集, 09 Jul. 1999, Not reviewed, No invitation

Importance of Ligand Phe-phenyl Group for Activation of Thrombin Receptor
FUJITA Tsugumi; NOSE Takeru; MATSUSHIMA Ayami; COSTA Tommaso; SHIMOHIGASHI Yasuyuki
Peptide science : proceedings of the ... Japanese Peptide Symposium, 01 Oct. 1998

Structural Essentials for Agonist-Antagonist Actions of Thrombin Receptor Tethered-Ligand
NOSE Takeru; FUJITA Tsugumi; MORITA Yuki; COSTA Tommaso; SHIMOHIGASHI Yasuyuki
Peptide science : proceedings of the ... Japanese Peptide Symposium, 01 Oct. 1998

トロンビン受容体を介する血小板凝集阻害ペプチドの分子設計
森田由紀; 藤田亜美; 野瀬健; 下東康幸
化学関連支部合同九州大会講演予稿集, Jul. 1998, Not reviewed, No invitation

Structural factors in acceptor binding of pain peptide nociceptin.
中島理恵; 畑野陵; 藤田亜美; 野瀬健; 朱雀鉄城; 西郷晶; 長久厚; 下東康幸
化学関連支部合同九州大会講演予稿集, Jul. 1997, Not reviewed, No invitation

Design and Synthesis of para-Fluorophenylalanine Amide Derivatives Containing N-Terminal Thiol as Thrombin Receptor Antagonist
FUJITA Tsugumi; NOSE Takeru; NAKAJIMA Masahide; INOUE Yoshihisa; SHIMOHIGASHI Yasuyuki; OHNO Motonori
Peptide chemistry : proceedings of the ... Symposium on Peptide Chemistry, 01 Oct. 1996

Platelet Aggregation Activity of Thrombin Receptor-Tethered Peptide Ligand Containing Free Thiol or Activated SH Group
NOSE Takeru; KAWAHARA Megumi; FUJITA Tsugumi; NAKAJIMA Masahide; INOUE Yoshihisa; NAKAMURA Norifumi; SHIMOHIGASHI Yasuyuki; OHNO Motonori
Peptide chemistry : proceedings of the ... Symposium on Peptide Chemistry, 01 Oct. 1996

トロンビン受容体内臓リガンドSFLLRNPの血小板凝集におけるC端側アミノ酸残基の重要性
藤田 亜美; 野瀬 健; 佐藤 祐介; 中島 政英; 井上 佳久; 下東 康幸; 大野 素徳
日本分子生物学会年会プログラム・講演要旨集, Aug. 1996, Not reviewed, No invitation

Thrombin receptor activation of the internal ligand analog with Cys(Npys) included.
河原恵; 野瀬健; 藤田亜美; 下東康幸; 大野素徳
化学関連支部合同九州大会講演予稿集, Jul. 1996, Not reviewed, No invitation

Design and Synthesis of Thrombin Receptor Antagonist Containing Acidic Amino Acids.
藤田亜美; 野瀬健; 下東康幸; 大野素徳
日本化学会講演予稿集, Mar. 1996, Not reviewed, No invitation

A Molecular Design of the Thrombin Receptor Antagonist
FUJITA Tsugumi; NOSE Takeru; SHIMOHIGASHI Yasuyuki; OHNO Motonori
Peptide chemistry : proceedings of the ... Symposium on Peptide Chemistry, 01 Oct. 1995

Molecular design of thrombin acceptor antagonist.
藤田亜美; 野瀬健; 下東康幸; 中島政英; 今田光昭; 井上佳久; 大野素徳
化学関連支部合同九州大会講演予稿集, Jul. 1995, Not reviewed, No invitation

脳とニューロンの生理学 : 情報伝達・発生・意識
小島 比呂志; 大谷 悟; 熊本 栄一; 仲村 春和; 藤田 亜美
丸善出版, 2014, Not reviewed
9784621086469

Peptide Science 2009
The Japanese Peptide Society (Osaka), 2010, Not reviewed

慢性疼痛における薬剤選定と治療薬開発
（株）技術情報協会（東京都）, 2010, Not reviewed

ガイトン生理学 原著第11版
エルゼビア・ジャパン株式会社（東京都）, 2010, Not reviewed
9784860347246

Peptide Science 2008
The Japanese Peptide Society (Osaka), 2009, Not reviewed

Cellular and Molecular Mechanisms for the Modulation of Nociceptive Transmission in the Peripheral and Central Nervous Systems
Research Signpost (Kerala, India), 2007, Not reviewed

Peptide Science 2005
The Japanese Peptide Society (Osaka), 2006, Not reviewed

Peptide Science 2006
The Japanese Peptide Society (Osaka), 2006, Not reviewed

Peptide Science 2004
The Japanese Peptide Society (Osaka), 2005, Not reviewed

Peptide Science 2001
The Japanese Peptide Society (Osaka), 2002, Not reviewed

Peptide Science 2000
The Japanese Peptide Society (Osaka), 2001, Not reviewed

Peptides: The Wave of the Future
American Peptide Society (San Diego, U.S.A.), 2001, Not reviewed

Peptide Science 1999
The Japanese Peptide Society (Osaka), 2000, Not reviewed

Peptide Science-Present and Future: Proceedings of the 1st International Peptide Symposium
Kluwer Academic Publishers (Dordrecht, The Netherlands), 1999, Not reviewed

Frontiers in Protein Chemistry and Biotechnology: Proceedings of the 3rd International Symposium on Frontiers in Protein Chemistry and Biotechnology
Changchung Publishing House (Changchung City, China), 1999, Not reviewed

Peptide Science 1998
Protein Research Foundation (Osaka), 1999, Not reviewed

Peptide Chemistry 1996
Protein Research Foundation (Osaka), 1997, Not reviewed

Peptide Chemistry 1995
Protein Research Foundation (Osaka), 1996, Not reviewed

Analysis of the regulation by orexins of nociceptive transmission in the spinal dorsal horn by using the patch-clamp technique
Grant-in-Aid for Scientific Research (C)
Saga University
01 Apr. 2015 - 31 Mar. 2018

Analysis of the action of oxytocin at synapse level in regulating nociceptive transmission in rat spinal dorsal horn
Grant-in-Aid for Scientific Research (C)
Saga University
01 Apr. 2012 - 31 Mar. 2015

Modulation by proteinase-activated receptor of TRP regulation of nociceptive transmission in the adult rat spinal dorsal horn
Grant-in-Aid for Young Scientists (B)
Saga University
28 Apr. 2011 - 31 Mar. 2015

Cellular mechanisms for the biphasic regulation by galanin of nociceptive transmission in the rat spinal dorsal horn
Grant-in-Aid for Scientific Research (C)
Saga University
2009 - 2011

Role of arachidonic acid cascade in regulating nociceptive transmission in the rat spinal dorsal horn
Grant-in-Aid for Scientific Research (C)
Saga University
2007 - 2008

Interacion between proteinase-activated receptors and TRP channels in regulating nociceptive transmission in the rat spinal dorsal horn
Grant-in-Aid for Young Scientists (B)
Saga University
2007 - 2008

Effect of phospholipase A2 activation on pain transmission in rat spinal dorsal horn neurons
Grant-in-Aid for Scientific Research (C)
Saga University
2005 - 2006

ラット脊髄後角における痛覚情報伝達に及ぼすプロテアーゼ受容体活性化の効果
若手研究(B)
佐賀大学
2004 - 2005

Role of cannabinoids in regulating nociceptive transmission in the rat spinal dorsal horn
Grant-in-Aid for Scientific Research (C)
Saga University
2002 - 2003

ラット脊髄後角痛覚情報伝達に対するエンドモルフィン作用の解析
若手研究(B)
佐賀大学(医学部)
2002 - 2003

ペプチドリガンド/受容体の疎水性相互作用の分子機構解析
特別研究員奨励費
九州大学
2000 - 2001

含フッ素フェニルアラニン導入ペプチドによるトロンビン受容体活性化機構の解明
特別研究員奨励費
九州大学
1998 - 1999

Joint Study on Molecular Mechanism of Opioid Receptors
Grant-in-Aid for Scientific Research (B).
KYUSHU UNIVERSITY
1997 - 1999